Buy Proviron steroid. Proviron is a modified form of dihydrotestosterone. Due to the addition of a methyl group at carbon 1, this drug differs from the dihydrotestosterone that protects hormones from metabolism in the liver while orally administered. In the orally taken tablets Primobolan (methenolone) the same structural modification is applied. Right after the first administration of the drug, the alkylation at the 1 position inhibits the hepatic metabolism of steroids, although to a much less extent than at c-17 alpha alkylation. Mesterolone is an androgen, as well as dihydrotestosterone, and its anabolic activity is manifested at a low level.
Mesterolone is sufficiently resistant to decay, thus achieving a therapeutically useful level in the blood, even despite the fact that the drug has a much lower total bioavailability than 17 alpha-alkylated steroids, which are used orally. Proviron has a fast period of recovery in the muscle tissue to inactive metabolites of diol, where the concentration of the 3-hydroxysteroid dehydrogenase enzyme is quite high.
Do not think that the weak anabolic nature of this compound blocks androgen receptors in muscle tissue, thereby reducing the beneficial effects of other steroids that have a strong potential to build muscles. In fact, Proviron affects the activity of other steroids, turning most of them into free form due to its unique, almost identical affinity for plasma proteins, such as globulin that binds sex hormones.
Athletes use Proviron at the time of intensive preparation for a competition or during the course of a diet aimed at weight reduction to increase androgen levels and, due to its ability to bind to the aromatase enzyme, thereby not giving them the opportunity to convert testosterone into estradiol, serving as an antiestrogen.
Proviron is one of the oldest androgenic anabolic steroids, one of the first drugs used in clinical practice for the treatment of hormonal disorders in men since 1934. Despite the fact that it was synthesized in the same years that testosterone propionate and methyltestosterone, it either could not be attributed to outdated drugs since due to its efficacy and safety, it is still actively used in clinical treatment.
In the case of mental and physical activity reduction, caused by natural aging, decreased libido appeared due to low levels of androgens, and for the treatment of hypogonadism in adolescents and aged men and infertility (the drug may increase the number and quality of sperm), it is recommended to use Proviron. However, the use of any androgenic anabolic steroids is a risk of infertility, and therefore the ability of the drug to give a positive result during the treatment is very contradictory. It is also known that many athletes take Proviron not correctly. When used in the recommended therapeutic dose, the drug does not significantly suppress the gonadotropins and also does not affect the release of luteinizing hormone.
Proviron is recommended to use in addition to androgens, which are necessary for sperm production. These androgens directly stimulate sperm production and affect sperm maturation and transport, due to impact on the seminal vesicles, vas deferens, and appendage. This process shows us that such hormones can perform not only a suppressive role. Due to the stimulation of sperm quality and quantity by Proviron which is not detected with suppression of gonadotropins, there are some cases when the medicament is used to treat male infertility.
Proviron has not received approval for sale in the United States, but because of its effectiveness and safety it is successfully sold in most countries, to be more precise, in more than thirty countries implement it in their territories. This drug can be found in the global pharmaceutical market under the names such as: Provi-Ron, Provironum, Mestoranum, Vistimon, Pluriviron, and Restore. At the moment, the main supplier of Proviron is a Schering company.
For females: It is not recommended to use the drug by females because of its high androgenic effect.
For males: The recommended dosage for males constitutes 50 to 200 mg/day.
A Proviron cycle should not exceed 12 weeks.
Proviron is referred to as a class of androgenic steroids. During the use of androgenic steroids side effects appear quite often.
Side effects in men due to testosterone use include alopecia, increasing hair growth on the body and face. Moreover, oily skin and acne may appear.
Side effects in females may occur in the form of increased growth of hair on the body and face, deepening of voice, periods’ irregularities, changes in skin texture, and clitoral enlargement. Also, the enzyme 5-alpha reductase does not metabolize mesterolone, so the administration of finasteride or dutasteride exerts no effect on its relative androgenicity.
Proviron does not cause any hepatotoxic side effects, due to the fact that it is not a C17 alpha alkaline compound, in other words, the toxicity in the liver is very low. Steroids of such class negatively affect the cholesterol level in the blood. This leads to a reduction of good cholesterol (HDL) levels and increase of bad cholesterol (LDL), which can lead to atherosclerosis.
The strength with which these steroids will affect serum lipids, depends directly on the dosage of the drug, the type of steroids, individual level of resistance to metabolism in the liver of specific organism and whether a drug is administered orally or by injection. Proviron does not aromatize and has no significant adverse effect on lipids.
Clinical studies have shown that the use of Proviron in a dosage of 100 mg / day during six months in men with hypogonadism resulted in a significant increase of total cholesterol levels by 18%. Thus LDL cholesterol increased by 65%, and HDL cholesterol decreased by 35%. Also, studies have shown that, usage of Proviron in a dosage less than 150 mg per day, it has actually no influence on the level of testosterone, but if daily dose exceeds 300 mg, the drug begins to suppress testosterone greatly.
If you have cardiovascular risk factors, which exclude the use of certain steroids orally, so it is not recommended to take Proviron. It is better to minimize the consumption of simple carbohydrates, saturated fats and cholesterol, and regular exercises while carrying out a full course of anabolic / androgenic steroids in order to reduce the risk of cardiovascular strain. Also, a combination of a drug with natural cholesterol drugs and antioxidants, fish oil or products with comparable ingredients exerts positive effect.
Proviron is not recommended for use in case of hypersensitivity to the active compound of the drug, the detection of liver tumors, and prostate cancer.
Proviron is actually a drug with anti-estrogenic activity. By blocking the estrogen receptors in the brain, it causes a surge in the release of the Gonadotropins (LH and FHS) which then induce the testes to make more testosterone.
The drug does not possess any direct anabolic or androgenic activity.
It was first synthesized in the 70s and by the late 90s had disappeared from the market. Schering the pharmaceutical company no longer makes the product. Every seller on the internet who claims they have the product is either not honest or is probably selling a fake product. There is no mass manufacture of this drug. While Proviron is available on cyberspace for sell, there are reports that the drug is smuggled in from in from Asia, Russia and Mexico. In all these cases, the authenticity of Proviron is in doubt.
It way initially tried out to treat both men and women who had depression and anxiety.
What was discovered in these studies was that the drug led to an increase in the Gonadotropins (LH & FSH) and increased testosterone levels. This then led to its use in the treatment of fertility problems. Today Proviron is no longer available and not used to treat any medical disorder. Almost without question, whatever is available on the internet is not Proviron and most likely fake or counterfeit.
Once upon a time, Proviron was indicated for the treatment of testosterone deficiency, and male infertility problems due to a problem in the hypothalamus, pituitary or testes
Proviron has more androgenic activity rather than anabolic effects. It is used by athletes and bodybuilders to help the body recover from the testosterone suppression that occurs after prolonged use of exogenous anabolic steroids.
The majority of bodybuilders who have used Proviron have been disappointed. The drug has failed to live up to the hype. Most users have claimed that the drug does not increase muscle mass or strength. In fact, the majority of individuals consider it a waste and unwarranted. Part of the problem may be due to the fact that the real Proviron is not available and perhaps people have been buying fake products. There are a lot of reports of counterfeit or fake Proviron products on the market. Unless the drug is tested in a chemistry laboratory it is impossible to tell what one is buying.
The drug does possess anti-estrogen activity like Nolvadex or Arimidex. Thus, it blocks the breast enlargement and water retention which are common side effects of most anabolic steroids.
Some users do claim that it causes the muscle to bulge and a rip- however, many of these users take so many other anabolic steroids; it is difficult to know which drug is actually responsible for the muscle growth. The drug has predominantly been used during the washout cycle to maintain the testosterone surge. Most knowledgeable athletes have stopped using Proviron and have turned instead to Arimidex or Nolvadex.
Proviron has also been used by females in the past. While there have been reports of its bodybuilding properties, there are just as many females who claim that the drug has done very little. Because of its anti-estrogen activity, all females who take this drug must be followed up by a health care professional.
Dose of Mesterolone is 25 mg by mouth 2-3 times a day for several months, followed by maintenance therapy for a few months. Proviron when taken orally is rapidly absorbed in the blood stream. It has a very long half life of close to 12-24 hours. It remains in the body for a long time and is easily detected in the urine for at least 2 weeks after the last dose.
Because the drug is not an effective anti-estrogen it is often combined with Tamoxifen or Arimidex. It is usually taken during the wash out phase.
Like any drug, Proviron also is associated with some rare side effects. While the side effects do not occur in all individuals, they are quite disturbing. The side effects include:
loss of libido
deepening of voice
acne, oily skin
Proviron is not recommended for use in:
in pregnant females
individuals with abnormal liver function
individuals who have prostate cancer
those who have allergies
The drug when available is expensive. What is in doubt is the quality and purity. All Proviron available today is available only on the black-market. The majority of the Proviron is smuggled into the US from Mexico and the Far East. One pill of 20 mg costs anywhere from $3-$4- and there is no way of telling if it is fake.
Proviron is a banned drug by most sports organizations. It is actively screened for in the urine. Because of its long half life, the drug is easily detected in the urine for up to 2 weeks after the last dose.
While it is not unlawful to possess Proviron, all sporting agencies to screen for it in the urine. In the USA, Proviron is classified under the control substance act as a schedule 3 drug.